The CHANG™ You Trust Is Back.
Same trusted formulations. Expanded support from Nexpring Health. Renewed confidence for your lab.
Irvine Scientific CHANG™ Cytogenetics Media is now part of Nexpring Health, bringing you the same trusted formulations for prenatal and oncology cytogenetics, now backed by expanded service, expertise, and global resources.
Because every culture counts.

Why Cytogenetics Labs Choose CHANG™ Media
Cytogenetic laboratories operate in demanding environments where cell culture performance is essential for accurate chromosome analysis and confident clinical reporting.
CHANG™ media solutions are designed to support the performance characteristics cytogenetics laboratories rely on, including reliable mitotic indices, high‑quality chromosome morphology, and clear, reproducible banding patterns across diverse sample types used in prenatal, oncology, and constitutional testing for both clinical diagnostics and research.

Reliable cell growth

Optimal chromosome morphology

High-quality metaphase spreads
A Trusted Partner for Cytogenetic Laboratories.
Built on Quality, Service, Trust, and Progress
✺ Service
Partnership beyond products with workflow specific support, lot reserves, and dependable follow-through.
✺ Quality
Rigorous manufacturing and quality control systems ensure reliable, reproducible performance, and lot-to-lot consistency.
✺ Trust
Built on decades of proven consistency, our unchanged formulations are trusted and preferred by laboratories worldwide.
✺ Progress
Continuous innovation focused on improving laboratory workflows and supporting the evolving needs of modern cytogenetics.
Reliable culture performance for oncology cytogenetics
CHANG™ Marrow is a complete, ready-to-use medium for the culture of human bone marrow cells. Based on IMDM and formulated with a unique blend of growth factors, it is optimized to support superior cell growth and morphology while helping improve the detection of abnormal cells critical to hematologic diagnosis and prognosis.


Increased mitotic index

Improved morphology

Fewer culture failures

Saves time and costs associated with testing
Cytogenetics Solutions Portfolio
A comprehensive portfolio of cytogenetic solutions designed to support laboratory workflows with consistency and reliability.

Reduce Prep. Reduce Variability. Gain Confidence.
Your team’s expertise is too valuable to be spent on routine media preparation. Switching to CHANG™ complete media can help simplify workflow, reduce handling complexity, and minimize variability associated with manual preparation. By lowering operational burden and easing QC demands, laboratories can free skilled staff to focus on high-value cytogenetic analysis.
- Less preparation time
- Less handling complexity
- Less variability from manual mixing
- More standardized workflow support











